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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T15249 | Estrogen receptor modulator 1 | Estrogen Receptor/ERR | |
Estrogen receptor modulator 1 causes regression of Tamoxifen-resistant, hormone-independent xenograft tumors. Estrogen receptor modulator 1 is an orally active and selective estrogen receptor modulator (SERM) (pIC50: 0.4... | |||
T40893 | Estrogen receptor modulator 6 | ||
Estrogen receptor modulator 6 (compound 3a) is a highly specific and potent agonist of the estrogen receptor (ER) β with a remarkable affinity (K i = 0.44 nM). This compound exhibits an impressive 19-fold selectivity for... | |||
T79064 | Estrogen receptor modulator 7 | Estrogen Receptor/ERR | |
Estrogen Receptor Modulator 7 is a potent modulator of estrogen receptors, utilized in cancer research [1]. | |||
T79109 | Estrogen receptor modulator 8 | Estrogen Receptor/ERR | |
Estrogen Receptor Modulator 8 (compound 4) is an orally active inhibitor targeting Estrogen Receptor/ERR α with potent efficacy (IC50 = 0.437 nM in MCF-7 cells) and effectively hampers MCF-7 cell proliferation (IC50 = 0.... | |||
T82439 | Estrogen receptor modulator 10 | Estrogen Receptor/ERR | |
Compound G-5b, an estrogen receptor modulator 10, functions as an estrogen receptor (ER) antagonist (IC50=6.7 nM) and degrader (DC50=0.4 nM). It has the capability to induce apoptosis and block cells at the G1/G0 phase, ... | |||
T7313 | Enclomiphene citrate | Enclomifene citrate,(E)-Clomiphene citrate,trans-Clomiphene citrate | Estrogen Receptor/ERR |
Enclomiphene citrate (trans-Clomiphene citrate) is a non-steroidal estrogen receptor antagonist,with antioestrogenic property | |||
T2544 | Bazedoxifene acetate | WAY-TES 424,TSE 424,WAY-140424 | Estrogen Receptor/ERR , Estrogen/progestogen Receptor |
Bazedoxifene acetate (WAY-TES 424) is a novel selective estrogen receptor modulator (SERM). | |||
T6404 | Bazedoxifene hydrochloride | Bazedoxifene HCl,TSE-424 | Estrogen Receptor/ERR , Estrogen/progestogen Receptor |
Bazedoxifene hydrochloride (TSE-424) is a novel, non-steroidal, indole-based estrogen receptor modulator (SERM) binding to both ERα and ERβ with IC50 of 23 nM and 89 nM, respectively. | |||
T12482 | Pipendoxifene hydrochloride | Estrogen Receptor/ERR | |
Pipendoxifene hydrochloride is a selective modulator of estrogen receptor. | |||
T5348 | SNG-1153 | Estrogen/progestogen Receptor | |
SNG-1153 is a estrogen receptor ER-alpha36 modulator. | |||
T21897L | MPP hydrochloride | MPP hydrochloride (289726-02-9 Free base) | Estrogen Receptor/ERR |
MPP hydrochloride is a selective estrogen receptor (ERR) modulator. | |||
T1193 | Clomiphene citrate | NSC 35770,Clomifene citrate | Estrogen Receptor/ERR , Estrogen/progestogen Receptor |
Clomiphene citrate (NSC 35770) is a selective estrogen receptor modulator. | |||
T27322 | Fispemifene | HM-101,HM 101,HM101 | Others |
Fispemifene (HM-101) is an estrogen receptor modulator (SERM) used to treat genitourinary syndromes and vaginal atrophy. | |||
T7839 | Lasofoxifene Tartrate | CP-336156 | Estrogen Receptor/ERR |
Lasofoxifene Tartrate (CP-336156) is a third-generation, non-steroidal selective estrogen receptor modulator. | |||
TQ0274 | 27-Hydroxycholesterol | 25(R)-27-hydroxy Cholesterol | Estrogen/progestogen Receptor , Liver X Receptor |
27-Hydroxycholesterol (25(R)-27-hydroxy Cholesterol) is a selective modulator of estrogen receptor and an agonist of the liver X receptor. | |||
T68042 | CHF-4227 | Chf4227,Chf 4227 | Estrogen Receptor/ERR |
CHF-4227 is a novel, potent and selective estrogen receptor modulator that reduces cholesterol and LDL cholesterol concentrations. | |||
T1549 | Raloxifene hydrochloride | LY156758 hydrochloride,Raloxifene HCl,LY139481 hydrochloride,Keoxifene hydrochloride,LY156758 (Keoxifene) HCl | Estrogen Receptor/ERR , Others , MAO , Estrogen/progestogen Receptor , Autophagy |
Raloxifene hydrochloride (LY156758 hydrochloride) is a second generation selective estrogen receptor modulator (SERM) used to prevent osteoporosis in postmenopausal women. It has estrogen agonist effects on bone and chol... | |||
T6743 | (E/Z)-4-Hydroxytamoxifen | Afimoxifene,4-Hydroxytamoxifen | Estrogen Receptor/ERR , Estrogen/progestogen Receptor |
(E/Z)-4-Hydroxytamoxifen (Afimoxifene) is the active metabolite of tamoxifen and a selective estrogen receptor (ER) modulator that is widely used in the therapeutic and chemopreventive treatment of breast cancer. | |||
T4420 | 4-Hydroxytamoxifen | ICI 79280,(Z)-4-hydroxy Tamoxifen,trans-4-Hydroxytamoxifen | Estrogen Receptor/ERR , Estrogen/progestogen Receptor |
4-Hydroxytamoxifen (ICI 79280) is the active metabolite of Tamoxifen, an estrogen receptor modulator (SERM) with selective and oral potency. 4-Hydroxytamoxifen has antitumor activity and may be used in breast cancer rese... | |||
T15248 | Estetrol | Donesta | Estrogen Receptor/ERR , Endogenous Metabolite |
Estetrol(Donesta) is an orally available, selective modulator of the estrogen receptor, a naturally occurring estrogen synthesized by the human fetal liver during pregnancy.Estetrol has effects on the endometrium or cent... |